Cohort studies1/30/2024 An exposed and a non-exposed group would first be identified e.g.) women presenting to a local county health department for prenatal care would be classified by smoking status – smokers and non-smokers.Ģ. How would you design a cohort study of the association between preterm delivery and cigarette smoking?ġ. Quantifying exposures includes information such as date of onset, frequency of exposure and duration and intensity of exposure. Techniques used to measure exposure include questionnaires (age, smoking habits), laboratory tests (cholesterol, hemoglobin), physical measurements (height, weight, blood pressure) and various special procedures (EKG, x-rays). Disadvantage of this type of study is that quality depends on the historical data that is available – both to define exposure and to identify the outcome. It can telescope the frame of calendar time for the study and obtain results sooner. In this case, the cohort is defined from historical data and followed up for disease up to the present time. Age of investigator may be a limiting factor Retrospective Cohort Study Disadvantages of this type of study include:ģ. The individuals are followed prospectively through time until disease develops or does not develop. In concurrent cohort study, the investigator identifies original study population at the beginning of the study. Retrospective Cohort Study (historical cohort or non-concurrent prospective study)īoth designs are identical, comparing exposed and non-exposed populations. Concurrent Cohort Study (prospective or longitudinal)Ģ.
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